| Date | Opponent | Venue | Home/Away | Time | Regis/Opp | |
|---|---|---|---|---|---|---|
| Nov 28 | (CYO Tournament) St. Edmunds | CYO/MIV Center | Away | 12:15 PM | 49 - 46 | |
| Nov 29 | (CYO Tournament) Moore Catholic | CYO/MIV Center | Away | 6:15 PM | 38 - 46 | |
| Dec 4 | Xaverian | Xaverian High School | Away | 5:00 PM | 34 - 55 | |
| Dec 6 | Holy Trinity | Holy Cross High School | Away | 1:00 PM | 52 - 33 | |
| Dec 8 | St. John Prep | St. John's Preparatory School | Away | 4:30 PM | - | |
| Dec 10 | Scanlan | Monsignor Scanlan High School | Away | 5:00 PM | 26 - 71 | |
| Dec 13 | Delbarton | Delbarton | Away | 5:00 PM | 39 - 51 | |
| Dec 16 | St. Raymond's | Regis High School | Home | 5:00 PM | 29 - 69 | |
| Dec 18 | Lasalle | Regis High School | Home | 4:00 PM | 48 - 45 | |
| Dec 22 | Kennedy Catholic | Kennedy Catholic | Home | 12:00 PM | 62 - 42 | |
| Jan 5 | Lasalle | Regis High School | Home | 4:30 PM | postponed | |
| Jan 9 | Salesian | Salesian High School | Away | 4:30 PM | 57 - 72 | |
| Jan 10 | Cardinal Hayes | Cardinal Hayes High School | Away | 2:00 PM | - | |
| Jan 14 | Spellman | Cardinal Spellman | Away | 4:30 PM | 43 - 33 | |
| Jan 15 | Iona Prep | Regis High School | Home | 4:30 PM | 37 - 70 | |
| Jan 17 | Spellman | Regis High School | Home | 3:30 PM | - | |
| Jan 18 | Molloy | Archbishop Molloy High School | Away | 1:00 PM | postponed | |
| Jan 23 | Xavier | Xavier High School | Home | 3:45 PM | 36 - 39 | |
| Jan 26 | Spellman | Regis High School | Home | 4:30 PM | postponed | |
| Jan 28 | Spellman | Regis - Upper Gym - Upper Gym | Home | 4:30 PM | 40 - 47 | |
| Jan 30 | Lasalle | La Salle Academy | Away | 4:15 PM | - | |
| Feb 2 | Lasalle | Regis - Upper Gym - Upper Gym | Home | 4:00 PM | - | |
| Feb 4 | St. Edmunds | Regis High School | Home | 5:00 PM | - | |
| Feb 5 | Kennedy Catholic | Regis High School | Home | 4:30 PM | - | |
| Feb 10 | Kennedy Catholic | Regis High School | Home | 4:30 PM | - | |
| Feb 12 | Molloy | Archbishop Molloy High School | Away | 4:30 PM | - | |
| Feb 14 | (CHSAA Playoff Begin) | Home | - | |||
| Feb 22 | (CHSAA Freshman Championship) | Home | - | |||